5-Amino-1MQ Powder (9g)
Molecular Formula: C10H11N2+
Molecular Weight: 159.21 g/mol
Synonyms: 5-Amino-1-Methylquinolinium, SCHEMBL6403148, CHEMBL4116828, ZMJBCEIHNOWCMC-UHFFFAOYSA-O, AKOS025269993
Research Applications:
- NNMT enzyme inhibition
- Metabolic and fat regulation studies
- Mitochondrial function and cellular energy balance
- Neurological and cognitive function research
Overview of 5-Amino-1MQ
5-Amino-1MQ is a small molecule that inhibits nicotinamide N-methyltransferase (NNMT), an enzyme linked to fat storage, insulin resistance, and metabolic dysfunction. By blocking NNMT activity, 5-Amino-1MQ has been studied for its role in cellular energy regulation, lipid metabolism, and muscle function. This compound is currently being researched for its potential applications in obesity, metabolic health, and neuroprotection.
5-Amino-1MQ and Fat Metabolism
Research suggests that NNMT inhibition may influence fat metabolism and energy expenditure. Key findings from metabolic studies indicate that:
- NNMT inhibition has been associated with reduced fat accumulation and adipocyte size
- Energy expenditure may be enhanced through alterations in lipid oxidation pathways
- Insulin sensitivity improvements have been observed in preclinical studies, suggesting potential applications in glucose regulation
Mitochondrial Function and Energy Regulation
Mitochondrial efficiency plays a crucial role in energy production. Studies suggest that 5-Amino-1MQ may support mitochondrial function by enhancing ATP generation and promoting fat oxidation. This could be relevant in research related to endurance, energy balance, and metabolic adaptations in various physiological conditions.
Impact on Gut Microbiome and Metabolism
Recent studies have explored how NNMT inhibition affects gut microbiota composition. Research suggests that:
- NNMT-inhibited models show distinct microbiome shifts, potentially influencing metabolic pathways
- Microbiome alterations may contribute to enhanced metabolic function and improved gut health
Neurological and Muscle Function Studies
Beyond metabolism, 5-Amino-1MQ is being studied for its effects on brain health and muscle performance. Emerging research suggests that:
- Cognitive function may benefit from NNMT inhibition through enhanced cellular energy regulation
- Muscle tissue may experience improved endurance and recovery through optimized metabolic pathways
Legal Disclaimer
This product is sold as a pure compound for research purposes only and is not intended for use as a dietary supplement. Please review our terms and conditions before purchasing.
Safety Information
Keep this product out of the reach of children. Research on 5-Amino-1MQ is still in progress, and improper handling may result in unintended effects. This product is not for human or veterinary use and is intended exclusively for laboratory research.
We ensure the highest standards for product quality and description but are not responsible for improper handling or application.
The information provided is for educational and informational purposes only. This compound has not been evaluated by the FDA and is not intended to diagnose, prevent, or treat any medical condition.

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